Clickable Linkers
Clickable linkers are bioorthogonal conjugation reagents designed for highly selective and efficient labeling, coupling, and bioconjugation under mild biological conditions. Widely used in chemical biology, targeted drug delivery, ADC development, and biomolecule labeling, clickable PEG linkers enable rapid and catalyst-free click chemistry reactions with high specificity and biocompatibility. Common clickable linker types include azide PEG linkers, alkyne PEG linkers, BCN linkers, DBCO PEG linkers, and tetrazine linkers for SPAAC and inverse electron-demand Diels–Alder (IEDDA) click chemistry applications.
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Azide and Alkyne Click Chemistry Linkers
Azide and alkyne click chemistry linkers are widely used bioorthogonal reagents for copper-catalyzed and copper-free click conjugation reactions. Commonly applied in biomolecule labeling, PEGylation, drug delivery, and chemical biology research, these clickable linkers enable efficient and selective conjugation with excellent biocompatibility and reaction specificity.
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BCN, DBCO, and Tetrazine Linkers
BCN, DBCO, and tetrazine linkers are advanced strain-promoted and bioorthogonal click chemistry reagents widely used in SPAAC and IEDDA conjugation applications. These highly reactive linkers support rapid, catalyst-free bioconjugation for antibody labeling, protein modification, targeted therapeutics, and in vivo imaging, making them essential tools in modern bioconjugation and chemical biology workflows.
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